Modified-Release Drug Delivery Technology, Second Edition
by Rathbone; Michael JohnEdition: 2nd
Format: Hardcover
Pub. Date: 2008-05-28
Publisher(s): CRC Press
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Summary
This two volume Second Editiondescribes the anatomical, physiological, pharmaceutical, and technological aspects of oral, colonic and rectal, ocular, oral mucosal, dermal and transdermal, nasal, vaginal, and pulmonary delivery routes, providing insight and critical assessment of the many available and emerging modified release drug delivery systems for their current and future value. Topics include:
Table of Contents
| Preface | p. v |
| Contributors | p. xi |
| Using Modified-Release Formulations to Maintain and Develop Markets | |
| The Modified-Release Drug Delivery Landscape: The Commercial Perspective | p. 1 |
| The Modified-Release Drug Delivery Landscape: Academic Viewpoint | p. 17 |
| The Modified-Release Drug Delivery Landscape: Advantages and Issues for Physicians and Patients | p. 35 |
| The Modified-Release Drug Delivery Landscape: Drug Delivery Commercialization Strategies | p. 49 |
| Ocular Technologies | |
| Ophthalmic Drug Delivery | p. 59 |
| Intraocular Implants for Controlled Drug Delivery | p. 85 |
| Bioadhesive Ophthalmic Drug Inserts (BODI) for Veterinary Use | p. 101 |
| Ion Exchange Resin Technology for Ophthalmic Applications | p. 109 |
| Injection and Implant Technologies | |
| Injections and Implants | p. 123 |
| Long-Acting Protein Formulation-PLAD Technology | p. 133 |
| Long-Term Controlled Delivery of Therapeutic Agents by the Osmotically Driven DUROS Implant | p. 143 |
| The SABER Delivery System for Parenteral Administration | p. 151 |
| Improving the Delivery of Complex Formulations Using the DepotOne Needle | p. 159 |
| ReGel Depot Technology | p. 171 |
| The Atrigel Drug Delivery System | p. 183 |
| Enhancing Drug Delivery by Chemical Modification | p. 191 |
| DepoFoam Multivesicular Liposomes for the Sustained Release of Macromolecules | p. 207 |
| ALZAMER Depot Bioerodible Polymer Technology | p. 215 |
| Pegylated Liposome Delivery of Chemotherapeutic Agents: Rationale and Clinical Benefit | p. 227 |
| Dermal and Transdermal Technologies | |
| Dermal and Transdermal Drug Delivery | p. 263 |
| ALZA Transdermal Drug Delivery Technologies | p. 273 |
| Microneedles for Drug Delivery | p. 295 |
| Transfersome: Self-Optimizing and Self-Driven Drug-Carrier, for Localized and Transdermal Drug Delivery | p. 311 |
| Advances in Wound Healing | p. 325 |
| Ultrasound-Mediated Transdermal Drug Delivery | p. 339 |
| Lipid Nanoparticles with Solid Matrix for Dermal Delivery: Solid Lipid Nanoparticles and Nanostructured Lipid Carriers | p. 349 |
| LidoSite-Vyteris Iontophoretic Technology | p. 373 |
| Nail Delivery | p. 383 |
| Immediate Topical Drug Delivery Using Natural Nano-Injectors | p. 395 |
| DOT Matrix Technology | p. 405 |
| The PassPort System: A New Transdermal Patch for Water-Soluble Drugs, Proteins, and Carbohydrates | p. 417 |
| Nasal Technologies | |
| Nasal Drug Delivery | p. 427 |
| Controlled Particle Dispersion: A Twenty-First-Century Nasal Drug Delivery Platform | p. 451 |
| DirectHaler Nasal: Innovative Device and Delivery Method | p. 469 |
| Vaginal Technologies | |
| Intravaginal Drug Delivery Technologies | p. 481 |
| Vaginal Rings for Controlled-Release Drug Delivery | p. 499 |
| Phospholipids as Carriers for Vaginal Drug Delivery | p. 511 |
| SITE RELEASE, Vaginal Bioadhesive System | p. 521 |
| Clindamycin Vaginal Insert | p. 531 |
| Bioresponsive Vaginal Delivery Systems | p. 539 |
| Pulmonary Technologies | |
| Pulmonary Delivery of Drugs by Inhalation | p. 553 |
| AERx Pulmonary Drug Delivery Systems | p. 563 |
| Formulation Challenges of Powders for the Delivery of Small Molecular Weight Molecules as Aerosols | p. 573 |
| Adaptive Aerosol Delivery (AAD) Technology | p. 603 |
| Nebulizer Technologies | p. 613 |
| Formulation Challenges: Protein Powders for Inhalation | p. 623 |
| The Respimat, a New Soft Mist Inhaler for Delivering Drugs to the Lungs | p. 637 |
| Pressurized Metered Dose Inhalation Technology | p. 647 |
| Dry Powder Inhalation Systems from Nektar Therapeutics | p. 659 |
| Technosphere/Insulin: Mimicking Endogenous Insulin Release | p. 673 |
| Index | p. 681 |
| Table of Contents provided by Ingram. All Rights Reserved. |
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