Genetics A Beginner's Guide
by Guttman, Burton; Griffiths, Anthony; Suzuki, David; Cullis, TaraFormat: Paperback
Pub. Date: 2002-11-01
Publisher(s): Oneworld Publications
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Summary
With genetics and genetic engineering receiving almost daily coverage in theedia, this book is an introduction for general readers who wish to know morebout a science that is changing our world. Starting with the history ofenetics, from primitive breeding programmes to Mendel's Law, and moving ono a full explanation of genetics and its role in our future, this is aomprehensive survey of genetics past, present and future.
Author Biography
Burton Guttman is a Professor of Biology at The Evergreen State College, Washington, USA.
Table of Contents
| Preface | p. ix |
| Genetics: past, present, and future | p. 1 |
| The search for order and meaning | p. 3 |
| The modern image of science | p. 5 |
| The prospects of modern genetics | p. 10 |
| From myth to modern science | p. 13 |
| Primitive interest in heredity | p. 15 |
| Mythology and the domestication of plants and animals | p. 16 |
| Heredity in human society | p. 20 |
| How are children made? | p. 23 |
| What is inherited? | p. 29 |
| Cellular structure | p. 30 |
| Molecular structure | p. 34 |
| Growth and biosynthesis | p. 41 |
| Enzymes | p. 43 |
| Synthesizing polymers | p. 46 |
| Cells as self-renewing, self-reproducing factories | p. 48 |
| The breakthrough: mendel's laws | p. 49 |
| Mendel's discoveries | p. 50 |
| Pedigrees | p. 53 |
| Another example: tasters and non-tasters | p. 58 |
| Blood types | p. 60 |
| Multiple alleles and dominance | p. 63 |
| Test crosses | p. 64 |
| Probability | p. 64 |
| Two or more genes | p. 66 |
| Mendel's first law and disputed paternity | p. 68 |
| Answers to blood types questions | p. 70 |
| Chromosomes, reproduction, and sex | p. 71 |
| Cells and reproduction | p. 71 |
| Mitosis and the cell cycle | p. 73 |
| Karyotypes | p. 75 |
| Meiosis | p. 76 |
| Meiosis explains Mendel | p. 82 |
| The location of genes | p. 83 |
| Sex chromosomes | p. 83 |
| Nondisjunction of chromosomes | p. 85 |
| XYY males: a genetic dilemma | p. 88 |
| The function of genes | p. 93 |
| Genes and metabolic disease | p. 93 |
| Genes and enzymes | p. 94 |
| Proteins and information | p. 97 |
| Modification of hereditary disease | p. 101 |
| The hereditary material, dna | p. 108 |
| Bacteria | p. 109 |
| The first clue | p. 111 |
| Bacteriophages | p. 114 |
| The Hershey--Chase experiment | p. 116 |
| DNA structure | p. 118 |
| Genetic implications | p. 122 |
| Testing DNA structure | p. 124 |
| The genetic dissection of gene structure | p. 127 |
| Gene arrangement | p. 127 |
| Crossing over within genes | p. 132 |
| Phage genetics | p. 134 |
| Fine structure of genes | p. 134 |
| Complementation and the definition of a gene | p. 135 |
| What is a gene? | p. 137 |
| Restriction enzymes and palindromes | p. 139 |
| Restriction mapping | p. 142 |
| Deciphering the code of life | p. 146 |
| How are proteins made? | p. 148 |
| RNA molecules: the tools for protein synthesis | p. 150 |
| RNA transcription | p. 152 |
| The translation process | p. 154 |
| The complexity of eucaryotic genes | p. 156 |
| Cracking the code | p. 159 |
| Colinearity of genes and proteins | p. 160 |
| Stop codons | p. 162 |
| Universality of the code | p. 163 |
| Heredity in the bacterial world | p. 164 |
| Mutant bacteria | p. 164 |
| Sex in E. coli | p. 165 |
| Plasmids | p. 168 |
| Resistance factors and antibiotic resistance | p. 168 |
| Lysogeny | p. 173 |
| Gene transfer by virus | p. 174 |
| Transduction in humans | p. 175 |
| Gene regulation and development | p. 179 |
| Bacterial gene regulation | p. 180 |
| Regulating eucaryotic genes | p. 184 |
| Embryonic development in general | p. 185 |
| Regulation by time in a chick's wing | p. 188 |
| Determination by position in a fly's body | p. 189 |
| Forming a fly's eye | p. 191 |
| Dna manipulation: the return of epimetheus? | p. 194 |
| Recombinant DNA and restriction enzymes | p. 195 |
| Studies of individual cloned fragments | p. 197 |
| Transgenic organisms | p. 200 |
| Human gene therapy | p. 203 |
| Genomics, the study of complete genomes | p. 205 |
| The geneticist as dr. frankenstein | p. 209 |
| The regulation of recombinant-DNA research | p. 209 |
| Genetically modified organisms | p. 213 |
| Technology in context | p. 215 |
| The arguments against producing GMOs | p. 217 |
| Cloning as an ethical target | p. 224 |
| The responsibility of scientists | p. 226 |
| The fountain of change: mutation | p. 229 |
| Mutation rates | p. 230 |
| Mutation in humans | p. 231 |
| Radiation | p. 232 |
| What are mutations like? | p. 235 |
| DNA repair systems | p. 238 |
| General effects of radiation | p. 239 |
| Chromosome aberrations | p. 242 |
| Looking at human chromosomes | p. 244 |
| Aneuploidy | p. 245 |
| Duplications and deficiencies | p. 246 |
| Inversions | p. 248 |
| Translocations | p. 249 |
| Evolutionary genetics | p. 251 |
| Evidence for evolution | p. 253 |
| Evolution as a process | p. 255 |
| Population genetics | p. 257 |
| Human evolution | p. 260 |
| The migration and diversification of Homo sapiens | p. 261 |
| Eugenics | p. 264 |
| Glossary | p. 268 |
| Notes | p. 288 |
| Further reading | p. 292 |
| Index | p. 294 |
| Table of Contents provided by Syndetics. All Rights Reserved. |
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