Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools
by Editor: Sean Ekins; Editor: Jinghai J. XuFormat: eBook
Pub. Date: 2009-01-01
Publisher(s): Wiley
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Summary
This book covers key emerging technologies - detailed under About the Topic - in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The cross-disciplinary collaborations implicit in integrating these technologies with drug discovery operations will fuel the engine for future innovations. This book cuts across the multiple areas of drug discovery, each chapter authored by pioneers in that field, making for a broad appeal to the chemical and biological scientists and technologists involved in drug discovery and development.
Table of Contents
| Preface | |
| Acknowledgments | |
| Contributors | |
| Drug Efficacy And Safety Technology | |
| Focus on Fundamentals: Towards Better Therapeutic Index Prediction | |
| High-Throughput Protein-Based Technologies and Computational Models for Drug Development, Efficacy and Toxicity | |
| Cellular Systems Biology Applied to Pre-Clinical Safety Testing: A Case Study of CellCiphrTM Profiling | |
| Systems Pharmacology, Biomarkers and Biomolecular Networks | |
| Zebrafish Models for Human Diseases and Drug Discovery | |
| Toxicity Pathways and Models: Mining for Potential Side Effects | |
| Computational Systems Biology Modeling of Dosimetry and Cellular Response Pathways | |
| Stem Cell Technology for Embryotoxicity, Cardiotoxicity and Hepatotoxicity Evaluation | |
| Telemetry Technology for Preclinical Drug Discovery and Development | |
| Biologics Technology | |
| Nanotechnology to Improve Oral Drug Delivery | |
| Functional Glycomics and the Future of Glycomic Drugs | |
| Modeling Efficacy and Safety of Engineered Biologics | |
| Regulation of Gene Expression by Small, Non-Coding RNAs: Practical Applications | |
| Future Perspective | |
| Future Perspectives of Biological Engineering in Pharmaceutical Research: The Paradigm of Modeling, Mining, Manipulation and Measurements | |
| Index | |
| Table of Contents provided by Publisher. All Rights Reserved. |
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