Development of Cardiovascular Systems: Molecules to Organisms,9780521560726

Development of Cardiovascular Systems: Molecules to Organisms

by
ISBN13: 9780521560726
ISBN10: 0521560721
Format: Hardcover
Pub. Date: 1998-01-13
Publisher(s): Cambridge University Press
List Price: $93.99

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Summary

This book is a unique overview of cardiovascular development from the cellular to the organ level across a broad range of species. The first section focuses on the molecular, cellular, and integrative mechanisms that determine cardiovascular development. The second section has eight chapters that summarise cardiovascular development in invertebrate and vertebrate systems. The third section discusses the effects of disease and environmental and morphogenetic influences on non-mammalian and mammalian cardiovascular development. It includes strategies for the management of congenital cardiovascular malformations in utero and postnatally. The book will interest graduate students and researchers who work in the fields of developmental biology, physiology, and molecular and paediatric cardiology.

Table of Contents

List of contributors x(3)
Foreword xiii
Constance Weinstein
Introduction: Why study cardiovascular development? 1(6)
Warren W. Burggren
Bradley B. Keller
The primacy of the developing cardiovascular system 1(1)
The rationale for this book 2(1)
The scope and content of this book 2(5)
Part I Molecular, cellular, and integrative mechanisms determining cardiovascular development 7(94)
1 Genetic dissection of heart development
7(11)
Jau-Nian Chen
Mark C. Fishman
Introduction
7(1)
Drosophila: The power of genetic screens in invertebrates
7(4)
The mouse: The power of gene knockout
11(3)
The zebra fish: The power of genetic screens of a vertebrate
14(3)
Summary
17(1)
2 Cardiac membrane structure and function
18(9)
Lynn Mahony
The developing sarcolemma
18(2)
The transverse tubule system
20(1)
Mitochondria
21(1)
The sarcoplasmic reticulum
21(1)
Resting and action potentials
22(1)
Excitation-contraction coupling
23(1)
Relaxation
24(2)
Conclusion
26(1)
3 Development of the myocardial contractile system
27(8)
Anne M. Murphy
Mechanisms for diversity in contractile protein isoforms
27(1)
The contractile process
28(6)
Conclusions and future directions
34(1)
4 Vasculogenesis and angiogenesis in the developing heart
35(8)
Robert J. Tomanek
Anna Ratajska
Precoronary events
35(1)
Precursor cells and early vascularization
36(2)
The coronary arterial system
38(1)
Postnatal vascular growth
39(1)
Regulation of coronary vascularization
40(2)
Unanswered questions
42(1)
5 Extracellular matrix maturation and heart formation
43(14)
Wayne Carver
Louis Terracio
Thomas K. Borg
Introduction
43(3)
Cardiac cushion formation
46(1)
Matrix receptors
47(1)
Cardiac cushion maturation
47(2)
Three-dimensional organization of heart cells
49(1)
Myofibrillogenesis
50(2)
Neonatal heart development
52(1)
Proteoglycans
52(3)
Conclusions and future directions
55(2)
6 Endothelial cell development and its role in pathogenesis
57(8)
Jackson Wong
Introduction
57(1)
Endothelial cell development
57(4)
The role of the extracellular matrix in pathogenesis
61(3)
The unanswered questions
64(1)
7 Embryonic cardiovascular function, coupling, and maturation: A species view
65(23)
Bradley B. Keller
Introduction: Scope and definitions
65(1)
Embryonic cardiovascular morphometry
66(2)
Embryonic cardiovascular functional maturation: An overview
68(1)
Atrial function
68(5)
Ventricular function
73(8)
Ventricular-vascular coupling
81(4)
Functional consequences of ventricular growth acceleration
85(1)
Functional consequences of ventricular growth deceleration
86(1)
Cardiovascular consequences of autonomic nervous maturation
86(1)
Embryonic cardiac mechanics
87(1)
Significance and future directions of research
87(1)
8 Hormonal systems regulating the developing cardiovascular system
88(13)
Makoto Nakazawa
Fusae Kajio
Introduction
88(1)
Catecholamines and their effects
89(5)
Atrial natriuretic peptide and its effects
94(2)
Endothelin-1
96(1)
Conclusions and future directions
97(4)
Part II Species diversity in cardiovascular development 101(126)
9 Evolution of cardiovascular systems: Insights into ontogeny
101(13)
Anthony P. Farrell
Introduction
101(1)
Common solutions to common problems
102(2)
The evolution of cardiovascular systems
104(2)
Vertebrate cardiovascular evolution
106(3)
Mammalian cardiac development
109(2)
Forming a divided heart
111(2)
The coronary circulation
113(1)
Future directions
113(1)
10 Morphogenesis of vertebrate hearts
114(13)
Jose M. Icardo
The origin of the heart and early morphogenesis
114(3)
Heart induction
117(1)
Heart differentiation
118(2)
Differentiation and morphogenesis
120(1)
The cardiac loop
120(5)
Unanswered questions and some critiques
125(2)
11 Invertebrate cardiovascular development
127(18)
Brian R. McMahon
George B. Bourne
Ka Hou Chu
Introduction
127(1)
Annelida
127(3)
Arthropoda
130(7)
Mollusca
137(3)
Echinodermata
140(2)
Hemichordata
142(1)
Urochordata
142(2)
Concluding remarks
144(1)
12 Piscine cardiovascular development
145(21)
Peter J. Rombough
Introduction
145(1)
Morphogenesis
145(8)
Physiology
153(8)
Adaptive responses
161(3)
Concluding remarks
164(2)
13 Amphibian cardiovascular development
166(17)
Warren W. Burggren
Regina Fritsche
Introduction
166(1)
Cardiovascular anatomy of amphibians
166(5)
Hemodynamic maturation
171(8)
Diffusive versus convective oxygen delivery in early amphibian embryos: Do vertebrate embryos need hearts?
179(1)
Developmental plasticity of the amphibian cardiovascular and respiratory systems
180(2)
A perspective on future research
182(1)
14 Reptilian cardiovascular development
183(10)
Stephen J. Warburton
Introduction
183(1)
Structural development of the circulatory system
184(4)
Extraembryonic vessels
188(1)
Erythrocyte and hemoglobin function
188(1)
Cardiovascular responses to hypoxia
189(1)
Reptilian development and insights into vertebrate embryonic cardiovascular function
190(3)
15 Avian cardiovascular development
193(18)
Hiroshi Tazawa
Ping-Chun Lucy Hou
Introduction
193(1)
Embryogenesis and development of the chick heart
194(2)
Developmental pattern of cardiovascular variables
196(8)
Model analysis of cardiovascular shunts and cardiac output in the late embryo
204(4)
Concluding remarks and perspective
208(3)
16 Mammalian cardiovascular development: Physiology and functional reserve of the fetal heart
211(16)
Kent L. Thornburg
George D. Giraud
Mark D. Reller
Mark J. Morton
Functional adaptations of fetal ventricles
211(5)
Adaptations of the fetal coronary tree
216(6)
Summary and future directions
222(5)
Part III Environment and disease in cardiovascular development 227(58)
17 Oxygen, temperature, and pH influences on the development of nonmammalian embryos and larvae
227(13)
Bernd Pelster
Introduction
227(1)
Hypoxia
227(7)
Temperature
234(4)
Salinity and pH
238(1)
Conclusion
238(2)
18 Modeling gas exchange in embryos, larvae, and fetuses
240(19)
Alan W. Pinder
Introduction
240(4)
Gas exchange models for developing vertebrates
244(13)
Summary and a perspective
257(2)
19 Principles of abnormal cardiac development
259(9)
Adriana C. Gittenberger-de Groot
Robert E. Poelmann
Introduction
259(1)
The paradox of the double-outlet right ventricle
259(7)
Future directions
266(2)
20 In utero and postnatal interventions for congenital cardiovascular malformations
268(13)
V. Mohan Reddy
Frank L. Hanley
Introduction
268(1)
Fetal cardiovascular physiology
268(2)
Transitional circulation
270(3)
Myocardial development
273(1)
Postnatal intervention
273(4)
In utero interventions
277(4)
21 Applying the science of cardiovascular development to congenital cardiovascular malformations
281(4)
Edward B. Clark
Introduction
281(1)
Cardiac development and the genetic etiology of congenital cardiovascular malformations
282(1)
Cardiovascular development and surgical therapy
282(1)
Cardiovascular development and opportunities for prevention of congenital cardiovascular malformations
283(2)
Epilogue: Future directions in developmental cardiovascular sciences 285(2)
Bradley B. Keller
Warren W. Burggren
References 287(64)
Systematic index 351(2)
Subject index 353

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