Cytotoxins and Immunotoxins for Cancer Therapy : Clinical Applications
by Kawakami, Koji; Aggarwal, Bharat B.; Puri, Raj K.Pub. Date: 2004-11-15
Publisher(s): Taylor & Francis
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Summary
This book presents state-of-the-art information on various cytotoxins and immunotoxins in a single resoruce. The editors bring together leading researchers to summarize their work and discuss clinical trial data concerning some of the most widely studied tumors. The book describes Pseudomonas exotoxin (PE)-based immunotoxins and presents the latest results from clinical trials for the treatment of recurrent glioblastoma and other human cancers. It reviews the role of ricin-based immunotoxins for the treatment of lymphoma, explores several DT-based immunotoxins, and details the preclinical and clinical development of the first FDA-approved cytotoxin.
Table of Contents
| Preface: An Overview of Immunotoxins and Cytotoxins in Clinical Trials | |
| Pseudomonas Exotoxin (Pe)-Based Immunotoxins/Cytotoxins | |
| Targeting of Pseudomonas Exotoxin-based Immunotoxins to Hematologic Malignancies | |
| Interleukin-4-targeted Cytotoxin for Recurrent Glioblastoma Therapy | |
| Interleukin-13 Receptors and Development of IL-13-Pseudomonas Exotoxin for Human Cancer Therapy | |
| Ricin-Based Immunotoxins/Cytotoxins | |
| Ricin Immunotoxins in Lymphomas | |
| Diphtheria Toxin | |
| Table of Contents provided by Publisher. All Rights Reserved. |
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